Services
At CompagOs, we are enhancing drug development with the power of Bon3OID™ in vitro models. Our goal is to empower researchers in developing breakthrough therapies.
The Problem
In the field of bone diseases, existing in vitro models often fail to accurately replicate human bone biology. This leads to poor translation of research findings into clinical applications.
The Solution
CompagOs offers basic research, drug efficacy and toxicity testing services on biologically relevant Bon3OID™ in vitro models crafted from human cells.
Basic Bon3OID™ Models
Osteoblast Model: Bon3OID™
Use case:
Testing drug efficacy on a mineralized bone model containing osteoblasts and osteocytes. Ideal for anabolic bone-targeting agents. Seeding other cell types on the model is possible.
Bone Remodelling Model: Bon3OID™-OC
Use case:
Testing drug efficacy or bone-toxicity on a mineralised bone model replicating the bone remodelling cycle with osteoblasts, osteoclasts, and osteocytes. Ideal for functional assessment of anabolic and catabolic bone-targeting agents, as well as toxicity-to-bone assessments of any drug. Seeding other cell types on the model is possible.
Osteoblast Model: Bon3OID™
Use case:
Testing drug efficacy on a mineralized bone model containing osteoblasts and osteocytes. Ideal for anabolic bone-targeting agents. Seeding other cell types on the model is possible.
Bone Remodelling Model: Bon3OID™-OC
Use case:
Testing drug efficacy or bone-toxicity on a mineralised bone model replicating the bone remodelling cycle with osteoblasts, osteoclasts, and osteocytes. Ideal for functional assessment of anabolic and catabolic bone-targeting agents, as well as toxicity-to-bone assessments of any drug. Seeding other cell types on the model is possible.
Customized Bon3OID™
Models
We can customize our Bon3OID™ models to tailor them specifically to your area of interest in bone disease.
Rare Bone Diseases
We can use cells from patients with Osteogenesis Imperfecta, Hypophosphatasia, and other conditions to create Bon3OID™ models with a diseased phenotype.
Cancer
We can seed cancer cells (e. g. breast, prostate, osteosarcoma) onto our basic Bon3OID™ models to recreate a tumor-like bone microenvironment.
Individual Requests
Specific needs require specific solutions. Get in touch with us to discuss special requests, including unique cell types, readouts, or disease phenotypes (e. g. rheumatoid arthritis, osteomyelitis, osteoporosis).
Our Breakthrough Advantage
Biologically Relevant in vitro Conditions
Reproducible and Scalable Technology
Customized Services
Our Breakthrough Advantage
Biologically Relevant in vitro Conditions
Reproducible and Scalable Technology
Customized Services
Cutting-Edge Bon3OID™ Features
Assessment
Methods
We can employ advanced technologies to thoroughly examine each Bon3OID™ model and assess drug efficacy, cell interaction, and more. Our assessment methods include:
MicroCT
Stiffness Measurement
Histology and Staining
Confocal Microscopy
Omics
MicroCT
Stiffness Measurement
Histology and Staining
Confocal Microscopy
Omics
MicroCT
Stiffness Measurement
Histology and Staining
Confocal Microscopy
Omics
Starting Your Journey with Our Bon3OID™ Models
Step 1
Discuss your project requirements with us.
Step 2
We create the Bon3OID™ models for your project.
Step 3
We perform assessments on the Bon3OID™ models and provide a comprehensive report to you.
Elevate the Success of Your Research Efforts to The Next Level
Related Resources
Deepen your understanding of our solutions and their applications. Find out more in our Resource Center featuring publications, brochures, and more.
